Best Medical Spas in Gainesville, FL

The 10 best-rated medical spas in Gainesville, FL average 5.0★ on Google across 4,909 reviews. Pure Aesthetics has the top rating (5.0★), and Spa Royale has the most reviews (1,282). Updated October 27, 2026.

10 companies that meet our bar: rated 4.5★ or higher on Google, with a meaningful review history (4,909 reviews combined) and currently operating. Request a call back and the company will phone you directly.

Pure Aesthetics logo
#1

Pure Aesthetics

5.0 ★★★★★ · 1,150 Google reviews
Medical spa · 217 NW 76 Dr, Gainesville, FL 32607

“Lana was super great! Walked me through my first chemical peel and made me feel very prepared to handle it lol. Everyone here is super friendly and lovely. The atmosphere here is really nice as well. If you have the…” — Google review

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Relax Salt Rooms logo
#2

Relax Salt Rooms

5.0 ★★★★★ · 316 Google reviews
Wellness center · 4936 NW 39th Ave Ste a, Gainesville, FL 32606

“I have taken advantage of the serenity of the salt room many times. It makes a great "experience" gift for friends, is near some great restaurants, and has a wonderful gift shop. Highly, highly, highly recommend!” — Google review

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Accent Aesthetics logo
#3

Accent Aesthetics

5.0 ★★★★★ · 279 Google reviews
Medical spa · 4340 Newberry Rd #301, Gainesville, FL 32607

“Wonderful caring staff. Starting with Julie, then Dr Webb. and performed what to me was a miracle. Made me feel positive about myself. I feel so very good about my treatment and can see big improvement. Dr Webb is a…” — Google review

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PRP Regeneration Specialists logo
#4

PRP Regeneration Specialists

5.0 ★★★★★ · 218 Google reviews
Medical spa · 216 NW 135th Way Ste 10, Jonesville, FL 32669

“After undergoing nerve oblation and pain medicine injections, the Stem Cell injections were a breeze, even without laughing gas that was offered. I would recommend PRP Regeneration Specialist to anyone experiencing…” — Google review

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Nirvana Day Spa logo
#5

Nirvana Day Spa

5.0 ★★★★★ · 191 Google reviews
Spa · Suburban Professional Center, 4509 NW 23rd Ave #4, Gainesville, FL 32606

“What an experience! Absolutely wonderful time. So relaxing and calming. Lacy knew exactly what she was doing. I had the hair scalp treatment and a facial. I was totally noodled.” — Google review

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Spa Royale logo
#6

Spa Royale

4.9 ★★★★★ · 1,282 Google reviews
Day spa · 910 NW 57th St, Gainesville, FL 32605

“Shae cares about my wellbeing. Her hands are magic in finding the places in my body that need attention. I always look forward to our monthly sessions.” — Google review

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Paradise MedSpa & Wellness Center logo
#7

Paradise MedSpa & Wellness Center

5.0 ★★★★★ · 169 Google reviews
Medical spa · 105 SW 140th Ct Ste 2, Jonesville, FL 32669

“Val was absolutely amazing. It was truly the best facial I’ve ever had!!! She really took her time and also gave the best massage 💆‍♀️” — Google review

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John W. Tyrone, MD, PLLC, Plastic Surgery logo
#8

John W. Tyrone, MD, PLLC, Plastic Surgery

4.9 ★★★★★ · 713 Google reviews
Plastic surgeon · 108 NW 76 Dr A, Gainesville, FL 32607

“I highly recommend using Dr. Tyrone and staff for all of your aesthetic needs. From my consultation to my surgery, he was very informative, polite, and honest. He was direct and to the point and gave me the results I…” — Google review

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Ageless Spa Center logo
#9

Ageless Spa Center

4.9 ★★★★★ · 468 Google reviews
Spa · 4780 NW 39th Ave Ste 7, Gainesville, FL 32606

“Tenli Parrish, my esthetician, is simply divine in technique, precision, and empathy. I would highly recommend her and this spa for any of your treatment services!” — Google review

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Skin Avenue Aesthetics logo
#10

Skin Avenue Aesthetics

5.0 ★★★★★ · 123 Google reviews
Medical spa · 4020 Newberry Rd Ste 100, Gainesville, FL 32607

“This is my go-to place for everything! They have such a welcoming and comforting environment, especially for someone like me who is terrified of needles. I highly recommend starting with a consultation. They are…” — Google review

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How we pick medical spas in Gainesville

We scan Google Maps for medical spa listings in and around Gainesville, keep only open businesses whose main category matches the service, and require a Google rating of at least 4.5 from at least 20 reviews. Companies are ordered by a confidence-weighted score that balances rating and review volume. We do not accept payment for placement.

Frequently asked questions

Who is the highest-rated medical spa in Gainesville?

Pure Aesthetics has the highest Google rating on our Gainesville list: 5.0 out of 5 from 1,150 reviews (as of October 27, 2026).

Which medical spa in Gainesville has the most reviews?

Spa Royale has the most Google reviews among the companies listed here: 1,282, with a 4.9★ average.

How are these medical spas chosen?

Only open Gainesville-area businesses whose Google category matches the service, rated at least 4.5★ from at least 20 Google reviews. They are ordered by a confidence-weighted score of rating and review volume. Placement is never paid.

Also in Gainesville: Test Prep